Normal dietary consumption and absorption of copper exceed the metabolic need, and homeostasis of this element is maintained exclusively by the biliary excretion of copper. Wilson’s disease is an inherited disorder in which defective biliary excretion of copper leads to its accumulation, particularly in liver and brain.
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Staging Systems for Endometrial Cancer
Staging is performed with the use of the International Federation of Gynecology and Obstetrics (FIGO) system and the tumor–node–metastasis (TNM) system.
Fibrosis-4 (FIB4) Scoring System for Liver Fibrosis
The FIB4 index was developed in 2006 by Sterling as a non-invasive method to diagnose liver fibrosis and combines aspartate aminotransferase (AST) levels, alanine aminotransferase (ALT) levels, platelet count, and age.
Edmonton Obesity Staging System (EOSS)
The Edmonton Obesity Staging System (EOSS) is a novel risk-stratification system that classifies obese individuals into 5 graded categories, based on their morbidity and health-risk profile.
Saint Elian Wound Score System for Diabetic Foot Ulcers
Foot ulcerations are among the most complex and heterogeneous complications in patients with diabetes. Skin ulcers need to be managed in different ways dependent on their etiology and pathogenesis.
The 10 Saint Elian Wound Score System (SEWSS) categories is helpful in guiding treatment decisions based on severity subcategories.
CT Colonography Reporting and Data System (C-RADS)
In 2005, the CT Colonography Reporting and Data System (C-RADS) was established to provide a means of classifying findings of CT colonography (CTC) and of applying the advantages of structured reporting to the setting of colorectal cancer screening.
Lung Reporting and Data System (Lung-RADS)
The Lung CT Screening Reporting and Data System (Lung-RADS) is an algorithm that can be used to classify lung nodules in patients with significant smoking histories.
Gynecologic Imaging Reporting and Data System (GI-RADS)
Transvaginal ultrasound is the main reference technique in the evaluation of adnexal masses. Based on the Breast Imaging Reporting and Data System (BIRADS) classification Amor et al. suggested adapting this system to gynecologic ultrasound for the evaluation of adnexal masses: Gynecologic Imaging Reporting and Data System (GI-RADS) and based on recognition patterns and criteria recommended by the IOTA group.
Histologic Scoring Systems for Chronic Liver Disease
Grading and staging refers to a semiquantitative assessment of the necroinflammatory activity (grade) and degree of fibrosis (stage) in relation to chronic hepatitis.
Alvarado Score for Acute Appendicitis
The use of the Alvarado scoring system, which includes clinical examination findings and laboratory values, is helpful in ruling out appendicitis. Scores range from 1 to 10, with higher scores indicating a greater risk of appendicitis. When the score is less than 4, appendicitis is uncommon, and imaging and other interventions can be avoided.