RIFLE, a newly developed international consensus classification for acute kidney injury, defines three grades of severity
|
Category |
GFR Criteria |
Urine Output (UO) Criteria |
|
|
Risk |
Increased creatinine x1.5 or GFR decrease > 25% |
UO < 0.5ml/kg/h x 6 hr |
High Sensitivity High Specificity |
|
Injury |
Increased creatinine x2 or GFR decrease > 50% |
UO < 0.5ml/kg/h x 12 hr |
|
|
Failure |
Increase creatinine x3 or GFR decrease > 75% |
UO < 0.3ml/kg/h x 24 hr or Anuria x 12 hrs |
|
|
Loss |
Persistent ARF = complete loss of kidney function > 4 weeks |
|
|
|
ESKD |
End Stage Kidney Disease (> 3 months) |
|
|
GFR; Glomerular Filtration Rate
ARF; Acute Renal Failure
ESKD; End Stage Kidney Disease
References:
- Bellomo R, Kellum JA, Mehta R, Palevsky PM, Ronco C. Acute Dialysis Quality Initiative II: the Vicenza conference. Curr Opin Crit Care. 2002 Dec;8(6):505-8. [Medline]
- Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P; Acute Dialysis Quality Initiative workgroup. Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004 Aug;8(4):R204-12. Epub 2004 May 24. [Medline]
Created: Nov 03, 2005
