Glucocorticosteroids are a product of the adrenal cortex and perform a staggering number of physiological effects essential for life. Their clinical use is largely predicated on their anti-inflammatory and immunosuppressive properties.
| Glucocorticoid | Approximate Equivalent dose (mg) | Half-life (Biologic) hours |
| Short-Acting | ||
| Cortisone | 25 | 8-12 |
| Hydrocortisone | 20 | 8-12 |
| Intermediate-Acting | ||
| Methylprednisolone | 4 | 18-36 |
| Prednisolone | 5 | 18-36 |
| Prednisone | 5 | 18-36 |
| Triamcinolone | 4 | 18-36 |
| Long-Acting | ||
| Betamethasone | 0,6 – 0,75 | 36-54 |
| Dexamethasone | 0,75 | 36-54 |
References:
- Zoorob RJ, Cender D. A different look at corticosteroids. Am Fam Physician. 1998 Aug;58(2):443-50. [Medline]
Created: Apr 5, 2005
