Primary (no other evident associated disease)
-
- Hereditary neutrophilia
- Chronic idiopathic neutrophilia
- Chronic myelogenous leukemia (CML) and other myeloproliferative diseases
- Familial myeloproliferative disease
- Congenital anomalies and leukemoid reaction
- Leukocyte adhesion deficiency (LAD)
- Familial cold urticaria and leukocytosis
Secondary
- Infection
- Stress neutrophilia
- Chronic inflammation
- Drug induced: Steroids, lithium, tetracycline, G-CSF.
- Nonhematologic malignancy
- Generalized marrow stimulation as in hemolysis
- Asplenia and hyposplenism
References:
- Kyono W, Coates TD. A practical approach to neutrophil disorders. Pediatr Clin North Am. 2002 Oct;49(5):929-71, viii. [Medline]
Created: Oct 23, 2005