The TIMI risk score, based upon data from 15,000 patients with an ST segment elevation myocardial infarction eligible for fibrinolytic therapy, is a simple arithmetic sum of eight independent predictors of mortality.
| TIMI Risk Score for STEMI | |
| Historical | |
| Age 65-74 >/= 75 |
2 points 3 points |
| DM/HTN or Angina | 1 point |
| Exam | |
| SBP < 100 | 3 points |
| HR > 100 | 2 points |
| Killip II-IV | 2 points |
| Weight < 67 kg | 1 point |
| Presentation | |
| Anterior STE or LBBB | 1 point |
| Time to rx > 4 hrs | 1 point |
| Risk Score = Total | (0-14) |
DM, diabetes mellitus; HTN, hypertension; SBP, systolic blood pressure; HR, heart rate; STE, ST elevation; LBBB, left bundle branch block; and rx, treatment.
| Risk Score | Odds of death by 30D* |
| 0 | 0.1 (0.1-0.2) |
| 1 | 0.3 (0.2-0.3) |
| 2 | 0.4 (0.3-0.5) |
| 3 | 0.7 (0.6-0.9) |
| 4 | 1.2 (1.0-1.5) |
| 5 | 2.2 (1.9-2.6) |
| 6 | 3.0 (2.5-3.6) |
| 7 | 4.8 (3.8-6.1) |
| 8 | 5.8 (4.2-7.8) |
| >8 | 8.8 (6.3-12) |
| * referenced to average mortality (95% confidence intervals) | |
References:
- Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E. TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for treatment of infarcting myocardium early II trial substudy. Circulation. 2000 Oct 24;102(17):2031-7.[Medline]
- Morrow DA, Antman EM, Parsons L, de Lemos JA, Cannon CP, Giugliano RP, McCabe CH, Barron HV, Braunwald E. Application of the TIMI risk score for ST-elevation MI in the National Registry of Myocardial Infarction 3. JAMA. 2001 Sep 19;286(11):1356-9.[Medline]
Created: Feb 18, 2007
