Definite diagnosis
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Clinical picture consistent with tuberculosis; bacteriologic confirmation (culture, gene probe/NAA + AFB smear); histologic findings
Probable diagnosis
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Clinical picture consistent with tuberculosis; exclusion of other diagnostic considerations; presence of highly specific tuberculosis (surrogate) marker
Likely diagnosis
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Clinical picture consistent with tuberculosis; exclusion of other diagnostic considerations; typical response to antituberculosis treatment (in absence of other treatment)
NOTE. AFB, acid-fast bacilli; NAA, nucleic acid amplification.
References:
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Glassroth J. Clinical considerations in designing trials of vaccines for tuberculosis. Clin Infect Dis. 2000 Jun;30 Suppl 3:S229-32. [Medline]
Created: Mar 04, 2008