Syndrome of inappropriate antidiuretic hormone ADH release (SIADH) is a condition defined by the unsuppressed release of antidiuretic hormone (ADH) from the pituitary gland or nonpituitary sources or its continued action on vasopressin receptors.
Criteria for Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
- Hypotonic hyponatremia
- Urine osmolality >100 mOsm per kg (100 mmol per kg)
- Absence of extracellular volume depletion
- Normal thyroid and adrenal function
- Normal cardiac, hepatic and renal function
References:
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Fried LF, Palevsky PM. Hyponatremia and hypernatremia. Med Clin North Am 1997;81:585-609. [Medline]
Created: Aug 09, 2008
