CKD is defined as kidney damage or glomerular filtration rate (GFR) <60 mL/min/1.73 m(2) for 3 months or more, irrespective of cause. Kidney damage in many kidney diseases can be ascertained by the presence of albuminuria, defined as albumin-to-creatinine ratio >30 mg/g in two of three spot urine specimens.
Chronic kidney disease classification based upon glomerular filtration rate and albuminuria
|GFR stages||GFR (mL/min/1.73 m2)||Terms|
|G1||≥90||Normal or high|
|G2||60 to 89||Mildly decreased|
|G3a||45 to 59||Mildly to moderately decreased|
|G3b||30 to 44||Moderately to severely decreased|
|G4||15 to 29||Severely decreased|
|G5||<15||Kidney failure (add D if treated by dialysis)|
|Albuminuria stages||AER (mg/day)||Terms|
|A1||<30||Normal to mildly increased (may be subdivided for risk prediction)|
|A2||30 to 300||Moderately increased|
|A3||>300||Severely increased (may be subdivided into nephrotic and nonnephrotic for differential diagnosis, management, and risk prediction)|
The cause of CKD is also included in the KDIGO revised classification but is not included in this table.
GFR: glomerular filtration rate; AER: albumin excretion rate; CKD: chronic kidney disease; KDIGO: Kidney Disease Improving Global Outcomes.
Prognosis of CKD by GFR and Albuminuria Categories
|Prognosis of CKD by GFR and Albuminuria Categories:
|Persistent albuminuria categories
Description and range
|Normal to mildly
|GFR categories (ml/min/ 1.73 m2)
Description and range
|G3a||Mildly to moderately
Green: low risk (if no other markers of kidney disease, no CKD); Yellow: moderately increased risk; Orange: high risk; Red, very high risk.
- National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002 Feb;39(2 Suppl 1):S1-266. [Medline]
- Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, Rossert J, De Zeeuw D, Hostetter TH, Lameire N, Eknoyan G. Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2005 Jun;67(6):2089-100. [Medline]
- Summary of Recommendation Statements. Kidney Int Suppl (2011). 2013 Jan;3(1):5-14. [Medline]
Created Feb 24, 2023.