Leishmania donovani and Leishmania infantum/Leishmania chagasi are responsible for most of the cases of visceral leishmaniasis.
infectious
Diagnostic Criteria for Cystic Fibrosis (CF)
The diagnosis of cystic fibrosis is based on clinical signs and symptoms consistent with the disease and objective evidence of cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction.
One or more typical phenotypic features of CF:
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Chronic sinopulmonary disease
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Characteristic gastrointestinal and nutritional abnormalities
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Salt loss syndromes
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Obstructive azoospermia
or
Classification of Fever of Unknown Origin (FUO)
FUO is body temperature ≥ 38.3° C (101° F) rectally that does not result from transient and self-limited illness, rapidly fatal illness, or disorders with clear-cut localizing symptoms or signs or with abnormalities on common tests such as chest x-ray, urinalysis, or blood cultures.
Unexplained Fever in Young Children
Clinical and laboratory “low risk” criteria for children younger than 3 months with fever and no focus of infection
Clinical criteria
- Born at term (gestational age >/= 37 weeks)with uncomplicated nursery stay
- Previously healthy infants
- Notoxic manifestations
- No focal bacterial infection (except otitis media)
Modified Duke Criteria for the Clinical Diagnosis of Infective Endocarditis (IE)
The diagnosis of infective endocarditis is generally based on clinical, microbiologic, and echocardiographic findings. The Duke criteria have sensitivity and specificity of more than 80% and are the reference criteria for diagnosis.