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ESPGHAN Revised Criteria for the Diagnosis of Celiac Disease (CD)

Celiac disease (CD) is a syndrome characterized by damage of the small intestinal mucosa caused by the gliadin fraction of wheat gluten and similar alcohol-soluble proteins (prolamines) of barley and rye in genetically susceptible subjects. Continue reading “ESPGHAN Revised Criteria for the Diagnosis of Celiac Disease (CD)”

ROME II Diagnostic Criteria for Functional Disorders of the Biliary Tract and the Pancreas

The diagnosis of a Functional Disorder of the Biliary Tract and Pancreas always presumes the absence of a structural or biochemical explanation for the symptoms.

E1. Gallbladder Dysfunction

Episodes of severe steady pain located in the epigastrium and right upper quadrant, and all of the following:

  1. Symptom episodes last 30 minutes or more, with pain-free intervals;
  2. Symptoms have occurred on one or more occasions in the previous 12 months;
  3. The pain is steady and interrupts daily activities or requires consultation with a physician;
  4. There is no evidence of structural abnormalities to explain the symptoms; and
  5. There is abnormal gallbladder functioning with regard to emptying. Continue reading “ROME II Diagnostic Criteria for Functional Disorders of the Biliary Tract and the Pancreas”

ROME II Diagnostic Criteria for Functional Disorders of the Anus and Rectum

The diagnosis of a Functional Disorder of the Anus and Rectum always presumes the absence of a structural or biochemical explanation for the symptoms.

F1. Functional Fecal Incontinence

Recurrent uncontrolled passage of fecal material for at least one month, in an individual with a developmental age of at least 4 years, associated with:

  1. Fecal impaction; or
  2. Diarrhea; or
  3. Nonstructural anal sphincter dysfunction.

Continue reading “ROME II Diagnostic Criteria for Functional Disorders of the Anus and Rectum”

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