Celiac disease (CD) is a syndrome characterized by damage of the small intestinal mucosa caused by the gliadin fraction of wheat gluten and similar alcohol-soluble proteins (prolamines) of barley and rye in genetically susceptible subjects.
Gastroenterology
ROME II Diagnostic Criteria for Functional Bowel Disorders
The diagnosis of a Functional Bowel Disorder always presumes the absence of a structural or biochemical explanation for the symptoms.
ROME II Diagnostic Criteria for Functional Disorders of the Biliary Tract and the Pancreas
The diagnosis of a Functional Disorder of the Biliary Tract and Pancreas always presumes the absence of a structural or biochemical explanation for the symptoms.
E1. Gallbladder Dysfunction
Episodes of severe steady pain located in the epigastrium and right upper quadrant, and all of the following:
- Symptom episodes last 30 minutes or more, with pain-free intervals;
- Symptoms have occurred on one or more occasions in the previous 12 months;
- The pain is steady and interrupts daily activities or requires consultation with a physician;
- There is no evidence of structural abnormalities to explain the symptoms; and
- There is abnormal gallbladder functioning with regard to emptying.
ROME II Diagnostic Criteria for Functional Disorders of the Anus and Rectum
The diagnosis of a Functional Disorder of the Anus and Rectum always presumes the absence of a structural or biochemical explanation for the symptoms.
F1. Functional Fecal Incontinence
Recurrent uncontrolled passage of fecal material for at least one month, in an individual with a developmental age of at least 4 years, associated with:
- Fecal impaction; or
- Diarrhea; or
- Nonstructural anal sphincter dysfunction.