Pyoderma gangrenosum (PG) is a reactive non-infectious inflammatory dermatosis falling under the spectrum of the neutrophilic dermatoses, which includes Sweet’s syndrome and Behcet’s syndrome. Continue reading “Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum (PG)”
The majority (50 to 80%) of Zika virus (ZIKV) infections are asymptomatic. Symptomatic ZIKV infection has an incubation period of 3 to 14 days and is a mild illness, with a duration of up to 1 week, that manifests as a rash, low-grade fever, arthralgia and myalgia, and conjunctivitis. Complications are infrequent, but when they occur, they are severe and may be fatal. Continue reading “Features of Congenital Zika Syndrome”
Vogt-Koyanagi-Harada disease (VKHD) is a bilateral, chronic granulomatous panuveitis associated with central nervous system, auditory, and integumentary manifestations. Continue reading “Revised Diagnostic Criteria of Vogt-Koyanagi-Harada Disease (VKHD)”
Once the clinical suspicion is established, the diagnosis is based on the combination of clinical, biochemical, endoscopic, histological and/or radiological criteria. Continue reading “Lennard-Jones Diagnostic Criteria of Crohn’s Disease (CD)”
Ulcerative colitis (UC) is a chronic immune-mediated inflammatory condition of the large intestine that is frequently associated with inflammation of the rectum but often extends proximally to involve additional areas of the colon. Once a diagnosis of UC is made, determining the severity of disease becomes important. Continue reading “Ulcerative Colitis Activity Index”
The combination of raised intracranial pressure, without hydrocephalus or mass lesion, normal cerebrospinal fluid (CSF) composition and where no underlying aetiology is found are accepted criteria for the diagnosis of IIH. Continue reading “Diagnostic Criteria for Idiopathic Intracranial Hypertension (IIH)”
Monitoring of Intracranial Pressure (ICP) is an invasive technique and has some associated risks. For a favorable risk-to-benefit ratio, ICP monitoring is indicated only in patients with significant risk of intracranial hypertension. Continue reading “Indications for Intracranial Pressure Monitoring”
Female sexual dysfunction (FSD) is a general term comprising several sexual health concerns that can be distressing for patients, including female sexual interest/arousal disorder, female orgasmic disorder, and genito-pelvic pain/penetration disorder. Continue reading “DSM-5 Criteria for Female Sexual Interest/Arousal Disorder”
Preeclampsia is a disorder of pregnancy associated with new-onset hypertension, which occurs most often after 20 weeks of gestation and frequently near term. Although often accompanied by new-onset proteinuria, hypertension and other signs or symptoms of preeclampsia may present in some women in the absence of proteinuria. Continue reading “Revised Diagnostic Criteria for Preeclampsia”
Tuberous sclerosis complex (TSC) is highly variable in clinical presentation and findings. Disease manifestations continue to develop over the lifetime of an affected individual. Accurate diagnosis is fundamental to implementation of appropriate medical surveillance and treatment. Continue reading “Updated Diagnostic Criteria for Tuberous Sclerosis Complex (TSC)”
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