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New Diagnostic Criteria Proposed for Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney disease. Enlarging cysts within the kidneys are the clinical hallmark of the disease. Renal manifestations include varying degrees of kidney injury, urinary tract infections, kidney stones, and hematuria. Extrarenal manifestations can include pain, hypertension, left ventricular hypertrophy, hepatic cysts, intracranial aneurysm, diverticulosis, and abdominal and inguinal hernias. Continue reading “New Diagnostic Criteria Proposed for Polycystic Kidney Disease”

Syndromes or Disease Entities That Have Been Associated with Polycystic Ovaries

A- Hyperandrogenism

o Steroidogenic enzyme deficiencies

§ Congenital adrenal hyperplasia

§ Aromatase deficiency

o Androgen-secreting tumors

§ Ovarian

§ Adrenal

o Exogenous androgens

§ Anabolic steroids

§ Transsexual hormone replacement

o Other

§ Acne

§ Idiopathic hirsutism

Continue reading “Syndromes or Disease Entities That Have Been Associated with Polycystic Ovaries”

Diagnostic Criteria in Polycystic Ovary Syndrome (PCOS)

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive-aged women. This syndrome is predominantly characterized by irregular menstrual cycles, hyperandrogenism, and characteristic findings on pelvic ultrasound. Women with PCOS also frequently suffer from metabolic dysfunction, obesity, infertility and are at an increased risk of pregnancy complications and long-term cardiovascular disease. Continue reading “Diagnostic Criteria in Polycystic Ovary Syndrome (PCOS)”

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