New Diagnostic Criteria Proposed for Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney disease. Enlarging cysts within the kidneys are the clinical hallmark of the disease. Renal manifestations include varying degrees of kidney injury, urinary tract infections, kidney stones, and hematuria. Extrarenal manifestations can include pain, hypertension, left ventricular hypertrophy, hepatic cysts, intracranial aneurysm, diverticulosis, and abdominal and inguinal hernias. Continue reading

Syndromes or Disease Entities That Have Been Associated with Polycystic Ovaries

A- Hyperandrogenism

o Steroidogenic enzyme deficiencies

§ Congenital adrenal hyperplasia

§ Aromatase deficiency

o Androgen-secreting tumors

§ Ovarian

§ Adrenal

o Exogenous androgens

§ Anabolic steroids

§ Transsexual hormone replacement

o Other

§ Acne

§ Idiopathic hirsutism

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Diagnostic Criteria in Polycystic Ovary Syndrome (PCOS)

Revised diagnostic criteria of PCOS

1999 criteria (both 1 and 2)

1. Chronic anovulation

2. Clinical and/or biochemical signs of hyperandrogenism, and exclusion of other aetiologies

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