Antiphospholipid antibody syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis, complications during pregnancy, and the presence of antiphospholipid antibodies (APL) in plasma.
Rheumatology
Gout Classification Criteria
Gout, which is characterized by deposition of monosodium urate monohydrate (MSU) in synovial fluid and other tissues, is the most common form of inflammatory arthritis.
2017 ACR–EULAR Classification Criteria for Primary Sjögren’s Syndrome
A diagnosis of primary Sjögren’s syndrome is often made on the basis of a classic triad of symptoms: dryness of the mouth and eyes, fatigue, and pain. Systemic complications, which are present in 30 to 40% of patients, may provide the first clues to the disease.
2010 Diagnostic Criteria of Fibromyalgia
This simple clinical case definition of fibromyalgia correctly classifies 88.1% of cases classified by the ACR classification criteria, and does not require a physical or tender point examination.
Diagnostic Criteria of Familial Mediterranean Fever (FMF)
The diagnosis of familial Mediterranean fever (FMF) is based upon three factors: typical clinical manifestations, a positive response to colchicine therapy, and genetic testing, although currently available tests do not detect all mutations associated with FMF.
Diagnosis of Inflammatory Myopathies
The diagnosis of the exact subtype of inflammatory myopathy is based on the combination of clinical history, tempo of disease progression, pattern of muscle involvement, muscle enzyme levels, electromyographic findings, muscle-biopsy analysis, and for some conditions, the presence of certain autoantibodies.
ILAR Classification Criteria for Juvenile Idiopathic Arthritis (JIA)
Juvenile idiopathic arthritis is a heterogeneous group of diseases characterised by arthritis of unknown origin with onset before age of 16 years.
Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)
Disease activity is assessed using a combination of the clinical history, physical examination, organ specific functional tests, and serologic studies.
Diagnostic Criteria for Reiter´s Syndrome or Reactive Arthritides (ReA)
Reactive arthritis (ReA) is an inflammatory arthritis that arises after certain types of gastrointestinal or genitourinary infections. It belongs to the group of arthritidies known as the spondyloarthropathies (SpAs). The classic syndrome is a triad of symptoms, including the urethra, conjunctiva, and synovium; however, the majority of patients do not present with this classic triad. In general, there are two forms of ReA, postvenereal (Chlamydia trachomatis [Ct]) and postdysentery (Salmonella, Shigella, Campylobacter, and Yersinia), but several other bacteria have been implicated as potential causes.
Diagnosis of Goodpasture’s Syndrome
Goodpasture’s syndrome is a rare disorder characterized by pulmonary hemorrhage, glomerulonephritis, and antiglomerular basement membrane antibodies.