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Diagnostic Criteria for Myeloid Neoplasms with Myelodysplasia

Myelodysplastic syndromes (MDS) are myeloid neoplasms characterized by clonal proliferation of hematopoietic stem cells, recurrent genetic abnormalities, myelodysplasia, ineffective hematopoiesis, peripheral-blood cytopenia, and a high risk of evolution to acute myeloid leukemia (AML). Continue reading “Diagnostic Criteria for Myeloid Neoplasms with Myelodysplasia”

Classification Criteria for Discoid Lupus Erythematosus (DLE)

No universally recognized classification criteria currently exist for discoid lupus erythematosus (DLE), which has led to problematic heterogeneity in observational and interventional clinical studies across the field. Continue reading “Classification Criteria for Discoid Lupus Erythematosus (DLE)”

Diagnostic Criteria for Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State

A diagnosis of diabetic ketoacidosis (DKA) requires the patient’s plasma glucose concentration to be above 250 mg per dL (although it usually is much higher), the pH level to be less than 7.30, and the bicarbonate level to be 18 mEq per L or less. Continue reading “Diagnostic Criteria for Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State”

Diagnostic Criteria for Premenstrual Dysphoric Disorder (PMDD)

The American Psychiatric Association (APA) focuses predominantly on psychiatric symptoms in its diagnostic criteria for premenstrual dysphoric disorder (PMDD). Symptoms can occur anytime between menarche and menopause. Continue reading “Diagnostic Criteria for Premenstrual Dysphoric Disorder (PMDD)”

Diagnostic Criteria for Premenstrual Syndrome (PMS)

Premenstrual disorders consist of psychiatric or somatic symptoms that develop within the luteal phase of the menstrual cycle, affect the patient’s normal daily functioning, and resolve shortly after menstruation. The luteal phase begins after ovulation and ends with the start of menstruation. The American Congress of Obstetricians and Gynecologists (ACOG) includes psychiatric and physical symptoms in describing premenstrual syndrome (PMS).

Continue reading “Diagnostic Criteria for Premenstrual Syndrome (PMS)”

Diagnostic Criteria for Familial Hypercholesterolemia (FH)

The clinical diagnosis of FH is founded on personal and family history, physical examination, and lipid concentrations. Three groups have developed clinical diagnostic tools for FH: the US MedPed Program, the Simon Broome Register Group in the United Kingdom, and the Dutch Lipid Clinic Network. Continue reading “Diagnostic Criteria for Familial Hypercholesterolemia (FH)”

DSM-5 Diagnostic Criteria for Panic Disorder

Panic Disorder (PD) is characterized by episodic, unexpected panic attacks that occur without a clear trigger. Panic attacks are defined by the rapid onset of intense fear (typically peaking within about 10 minutes) with at least four of the physical and psychological symptoms in the DSM-5 diagnostic criteria. Continue reading “DSM-5 Diagnostic Criteria for Panic Disorder”

New Diagnostic Criteria Proposed for Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney disease. Enlarging cysts within the kidneys are the clinical hallmark of the disease. Renal manifestations include varying degrees of kidney injury, urinary tract infections, kidney stones, and hematuria. Extrarenal manifestations can include pain, hypertension, left ventricular hypertrophy, hepatic cysts, intracranial aneurysm, diverticulosis, and abdominal and inguinal hernias. Continue reading “New Diagnostic Criteria Proposed for Polycystic Kidney Disease”

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