Rheumatology – MedicalCRITERIA.com

Psoriasis Area Severity Index (PASI) Score

10 April, 2024 Guillermo Firman

The Psoriasis Area Severity Index (PASI) is a tool used to measure the severity of psoriasis, a chronic autoimmune skin condition characterized by red, scaly patches on the skin. PASI takes into account the extent of psoriatic involvement (area) as well as the severity of erythema (redness), induration (thickness), and desquamation (scaling) present within the involved regions. It provides a quantitative assessment of psoriasis severity and is commonly used in clinical trials and practice to monitor disease progression and treatment efficacy. Continue reading “Psoriasis Area Severity Index (PASI) Score”

Diagnostic Criteria for Rheumatoid Cachexia

12 April, 2023 Guillermo Firman

Cachexia in RA (rheumatoid cachexia, RC), is mainly characterized by loss of muscle mass, in particular appendicular lean mass (ALM), and associated with accumulated fat mass (FM), situated mainly in the trunk area, indicating a shift towards the development of abdominal obesity. The loss of body cell mass (BCM) consists of an important issue of concern for patients with RA. BCM consists primarily of muscle and visceral mass (erythrocytes, serum proteins, lymphocytes, etc.), and is the part of the body with the greatest metabolic activity (95% of the total activity), determining protein requirements, energy expenditure, and the metabolic response to stress.

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Sydney Classification Criteria for Definite Antiphospholipid Syndrome (APS)

13 September, 2021 Guillermo Firman

The antiphospholipid syndrome (APS) is characterized by thrombotic and/or pregnancy morbidity associated with the presence of persistent antiphospholipid antibodies (aPLs). There are many other clinical manifestations associated with persistent aPL (including immune thrombocytopenia, livedo reticularis, migraine, valvular heart disease and cognitive dysfunction). Continue reading “Sydney Classification Criteria for Definite Antiphospholipid Syndrome (APS)”

EULAR/ACR New Classification Criteria for Systemic Lupus Erythematosus (SLE)

12 March, 2021 Guillermo Firman

The new EULAR/ACR classification criteria use anti-nuclear antibodies (ANA) as an entry criterion. (Non-infectious) fever is the one new criterion. All criteria items now have individual weights (from 2 to 10) and are structured in domains, within which only the highest item is counted. There is one common attribution rule, counting criteria only if there is no more likely alternative explanation. Ten points are sufficient for classification. The new criteria have reached a sensitivity of 96.1% and a specificity of 93.4%. Continue reading “EULAR/ACR New Classification Criteria for Systemic Lupus Erythematosus (SLE)”

Classification Criteria for IgG4-Related Disease

14 January, 2021 Guillermo Firman

Immunoglobulin G4-related disease is an immune mediated condition resulting in disease in various organs of the body such as the pancreas, kidneys, salivary glands, lung, liver, lymph nodes, biliary tract and orbits of the eyes. The disease is recognized by a characteristic pattern of pathological, serological or clinical features shared amongst the organs system that are involved. In some cases, IgG4-RD can mimic malignant, infectious or inflammatory disorders and therefore distinguishing the disease is crucial. Continue reading “Classification Criteria for IgG4-Related Disease”

Classification Criteria for Discoid Lupus Erythematosus (DLE)

20 November, 2020 Guillermo Firman

No universally recognized classification criteria currently exist for discoid lupus erythematosus (DLE), which has led to problematic heterogeneity in observational and interventional clinical studies across the field. Continue reading “Classification Criteria for Discoid Lupus Erythematosus (DLE)”

2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

24 June, 2020 Guillermo Firman

Chapel Hill Consensus Conference (CHCC) is a nomenclature system (nosology). It is neither a classification system that specifies what findings must be observed in a specific patient to classify that patient for clinical research nor a diagnostic system that directs clinical management. Continue reading “2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides”

Revised Diagnostic Criteria of Vogt-Koyanagi-Harada Disease (VKHD)

9 October, 2019 Guillermo Firman

Vogt-Koyanagi-Harada disease (VKHD) is a bilateral, chronic granulomatous panuveitis associated with central nervous system, auditory, and integumentary manifestations. Continue reading “Revised Diagnostic Criteria of Vogt-Koyanagi-Harada Disease (VKHD)”

ASAS Categorization Criteria for Spondyloarthritis

23 August, 2019 Guillermo Firman

Assessment in SpondyloArthritis international Society (ASAS) criteria were validated in an international cohort trial with a sensibility and specificity close to 82.9 and 84.4%, respectively. Continue reading “ASAS Categorization Criteria for Spondyloarthritis”

Diagnostic Criteria for Primary Raynaud’s Phenomenon (RP)

16 August, 2019 Guillermo Firman

Raynaud’s phenomenon (RP), is a disorder of the microvasculature that generally affects the fingers and toes but can present on other extremities such as the nose, ears and nipples. Continue reading “Diagnostic Criteria for Primary Raynaud’s Phenomenon (RP)”

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