Appropriate Indications for Upper Gastrointestinal Endoscopy (UGE)

Upper gastrointestinal endoscopy is a standard technique that provides direct visualization of the gastrointestinal tract from the esophagus through the stomach, duodenal bulb, and descending duodenum.

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Revised Criteria for Hereditary Non-Polyposis Colorectal Cancer (Lynch Syndrome)

Amsterdam Criteria (1991)

Three or more relatives with colorectal cancer, plus all of the following:

  • One affected patient should be a first-degree relative of the other two;

  • Colorectal cancer should involve at least two generations;

  • At least one case of colorectal cancer should have been diagnosed before the age of 50 years.

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ROME II Diagnostic Criteria for Childhood Functional Gastrointestinal Disorders

The diagnosis of a Childhood Functional Gastrointestinal Disorder always presumes the absence of a structural or biochemical explanation for the symptoms.

G1.Vomiting

G1a. Infant Regurgitation

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ESPGHAN Revised Criteria for the Diagnosis of Celiac Disease (CD)

Celiac disease (CD) is a syndrome characterized by damage of the small intestinal mucosa caused by the gliadin fraction of wheat gluten and similar alcohol-soluble proteins (prolamines) of barley and rye in genetically susceptible subjects.

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ROME II Diagnostic Criteria for Functional Disorders of the Biliary Tract and the Pancreas

The diagnosis of a Functional Disorder of the Biliary Tract and Pancreas always presumes the absence of a structural or biochemical explanation for the symptoms.

E1. Gallbladder Dysfunction

Episodes of severe steady pain located in the epigastrium and right upper quadrant, and all of the following:

  1. Symptom episodes last 30 minutes or more, with pain-free intervals;
  2. Symptoms have occurred on one or more occasions in the previous 12 months;
  3. The pain is steady and interrupts daily activities or requires consultation with a physician;
  4. There is no evidence of structural abnormalities to explain the symptoms; and
  5. There is abnormal gallbladder functioning with regard to emptying.

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ROME II Diagnostic Criteria for Functional Disorders of the Anus and Rectum

The diagnosis of a Functional Disorder of the Anus and Rectum always presumes the absence of a structural or biochemical explanation for the symptoms.

F1. Functional Fecal Incontinence

Recurrent uncontrolled passage of fecal material for at least one month, in an individual with a developmental age of at least 4 years, associated with:

  1. Fecal impaction; or
  2. Diarrhea; or
  3. Nonstructural anal sphincter dysfunction.

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