Diagnosis, Clinical Characteristics, and Treatment of Sarcoidosis

Diagnosis

  • Diagnosis of sarcoidosis is firm when chest radiographic evidence is accompanied by compatible clinical features and noncaseating granulomas on biopsy, with all other causes of granulomas ruled out.
  • Biopsy is indicated for all patients presumed to have sarcoidosis, except those with Löfgren’s syndrome.

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Diagnostic Criteria for Preeclampsia

Preeclampsia: For the diagnosis of preeclampsia, both hypertension and proteinuria must be present.

  • Blood pressure: 140 mm Hg or higher systolic or 90 mm Hg or higher diastolic after 20 weeks of gestation in a woman with previously normal blood pressure. Systolic increased > 30 mm Hg or diastolic increased > 15 mm Hg in a patient with preexisting chronic hypertension.
  • Proteinuria: 0.3 g or more of protein in a 24-hour urine collection (usually corresponds with 1+ or greater on a urine dipstick test)

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Diagnostic Criteria for Acute Pharyngitis

Adults

Clinical suspicion of streptococcal pharyngitis (e.g., fever, tonsillar swelling, exudate, enlarged/tender anterior cervical lymph nodes, absence of cough or coryza) with

  • History of rheumatic fever or
  • Documented household exposure or
  • Positive rapid strep screen

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