Osteoporosis is defined as a metabolic bone disease “characterized by low bone mass and microarchitectural deterioration of bony tissue leading to enhanced bone fragility and a consequent increase in fracture risk.
Classification Criteria for Osteoarthritis
ACR Classification Criteria for Osteoarthritis of the Hip
Traditional format
Hip pain plus at least two of the following:
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ESR of less than 20 mm per hour
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Femoral or acetabular osteophytes on radiographs
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Joint space narrowing on radiographs
Classification of Neutrophilia
Primary (no other evident associated disease)
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- Hereditary neutrophilia
- Chronic idiopathic neutrophilia
- Chronic myelogenous leukemia (CML) and other myeloproliferative diseases
- Familial myeloproliferative disease
- Congenital anomalies and leukemoid reaction
- Leukocyte adhesion deficiency (LAD)
- Familial cold urticaria and leukocytosis
Classification of Neutropenia
Acquired neutropenia
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- Postinfectious: varicella, measles, rubella, hepatitis A and B, mononucleosis, influenza, cytomegalovirus, parvovirus, acquired immunodeficiency syndrome (AIDS), S. aureus, brucellosis, tularemia, rickettsia, Mycobacterium tuberculosis, sepsis.
- Drug induced: Antineoplastic agents, procainamide, antithyroid drugs, sulphasalazine, phenothiazines, semisynthetic penicillins, nonsteroidal anti-inflammatory agents, aminopyrine derivatives, benzodiazepines, barbiturates, gold compounds, sulfonamides, propranolol, dipyridamole, digoxin, acetyldigoxin, sulfamethoxizole, anticonvulsants
- Benign familial neutropenia
- Chronic benign neutropenia of childhood
- Chronic idiopathic neutropenia
- Autoimmune neutropenia
- Isoimmune neutropenia
- Neutropenia associated with immunologic abnormalities
- Neutropenia associated with metabolic diseases
- Neutropenia due to increased margination
- Nutritional deficiency
ICHD-II Diagnostic Criteria for Classical Trigeminal Neuralgia
Classical trigeminal neuralgia
A. Paroxysmal attacks of pain lasting from a fraction of a second to 2 minutes, affecting one or more divisions of the trigeminal nerve and fulfilling criteria B-C
B. Pain has at least 1 of the following characteristics:
Clinical Features of Nephrotic and Nephritic Syndrome
Clinical Features of Nephrotic Syndrome
The nephrotic syndrome is a clinical complex characterized by:
- proteinuria of >3.5 g per 1.73 m2 per 24 h (in practice, >3.0 to 3.5 g per 24 h),
- hypoalbuminemia,
- edema,
- hyperlipidemia,
- lipiduria, and
- hypercoagulability.
Diagnostic Criteria for Multiple Myeloma
Presence of an M-componenta in serum and/or urine plus clonal plasma cells in the bone marrow and/or a documented clonal plasmacytoma.
FAB Classification of Myelodysplastic Syndromes (MDS)
Refractory anemia (RA).
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Cytopenia of at least one lineage in the peripheral blood (usually anemia)
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Normal or hypercellular bone marrow with dysplastic changes
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Less than 1 percent blasts in the peripheral blood and less than 5 percent blasts in the bone marrow
Diagnostic Criteria for Myasthenia Gravis
Neuromuscular transmission disorder characterized by fluctuating weakness and fatigability of bulbar and other voluntary muscles without loss of reflexes or impairment of sensation or other neurologic function.
Knaus Criteria for Multiple System Organ Failure (MSOF)
Multiple systems organ failure is said present when more than one of the system dysfunctions detected by test values exceeding the threshold values.