In acetaminophen-induced fulminant hepatic failure, survival correlated with arterial blood pH, peak prothrombin time, and serum creatinine–a pH less than 7.30, prothrombin time greater than 100 s, and creatinine greater than 300 mumol/L indicating a poor prognosis.
Criteria
Histological Scoring System for Nonalcoholic Fatty Liver Disease (NAFLD)
Components of NAFLD Activity Score (NAS) and Fibrosis Staging
Child-Pugh Classification of Severity of Liver Disease
Modified Child-Pugh classification of severity of liver disease according to the degree of ascites, the plasma concentrations of bilirrubin and albumin, the prothrombin time, and the degree of encephalopathy.
Diagnosis of Visceral Leishmaniasis (Kala-Azar)
Leishmania donovani and Leishmania infantum/Leishmania chagasi are responsible for most of the cases of visceral leishmaniasis.
Diagnostic Criteria and Associated Features of Restless Legs Syndrome (RLS)
Restless legs syndrome (RLS), also called Willis-Ekbom Disease, causes unpleasant or uncomfortable sensations in the legs and an irresistible urge to move them.
Definition and Stages of Chronic Kidney Disease (CKD)
NKF Definition of Chronic Kidney Disease
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Kidney damage for three or more months, as defined by structural or functional abnormalities of the kidney, with or without decreased GFR, manifested by pathologic abnormalities or markers of kidney damage, including abnormalities in the composition of the blood or urine or abnormalities in imaging tests
- GFR < 60 mL per minute per 1.73 m2 for three months or more, with or without kidney damage
Diagnostic Criteria for Kawasaki Disease (KD)
Kawasaki disease (KD) is a childhood vasculitis affecting the medium-sized muscular arteries, mainly the coronary arteries. The hallmark of KD is fever lasting 5 days or more, counting the day of fever onset as day 1, in addition to 4 or 5 of the principal clinical criteria: cracking of lips or strawberry tongue, nonpurulent conjunctivitis, rash, erythema and edema of the hands and feet, and large unilateral cervical lymphadenopathy.
Pharmacokinetics of Insulin Preparations
Each insulin preparation has a different pharmacokinetic profile, i.e., onset, peak effect, and duration.
ICSD Revised Classification of Adult Insomnia
Primary Insomnia
- Idiopathic insomnia: Insomnia arising in infancy or childhood with a persistent, unremitting course
- Psychophysiologic insomnia: Insomnia due to a maladaptive conditioned response in which the patient learns to associate the bed environment with heightened arousal rather than sleep; onset often associated with an event causing acute insomnia, with the sleep disturbance persisting despite resolution of the precipitating factor
- Paradoxical insomnia (sleep-state misperception): Insomnia characterized by a marked mismatch between the patient’s description of sleep duration and objective polysomnographic findings
New Diagnostic Criteria for Myocardial Infarction (MI)
Criteria for acute, evolving or recent MI
Either one of the following criteria satisfies the diagnosis for an acute, evolving or recent MI:
1) Typical rise and gradual fall (troponin) or more rapid rise and fall (CK-MB) of biochemical markers of myocardial necrosis with at least one of the following: