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King´s College Hospital Criteria for Liver Transplantation in Fulminant Hepatic Failure

In acetaminophen-induced fulminant hepatic failure, survival correlated with arterial blood pH, peak prothrombin time, and serum creatinine–a pH less than 7.30, prothrombin time greater than 100 s, and creatinine greater than 300 mumol/L indicating a poor prognosis. Continue reading “King´s College Hospital Criteria for Liver Transplantation in Fulminant Hepatic Failure”

Child-Pugh Classification of Severity of Liver Disease

Modified Child-Pugh classification of severity of liver disease according to the degree of ascites, the plasma concentrations of bilirrubin and albumin, the prothrombin time, and the degree of encephalopathy.

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Diagnostic Criteria and Associated Features of Restless Legs Syndrome (RLS)

Restless legs syndrome (RLS), also called Willis-Ekbom Disease, causes unpleasant or uncomfortable sensations in the legs and an irresistible urge to move them.
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Definition and Stages of Chronic Kidney Disease (CKD)

NKF Definition of Chronic Kidney Disease

  • Kidney damage for three or more months, as defined by structural or functional abnormalities of the kidney, with or without decreased GFR, manifested by pathologic abnormalities or markers of kidney damage, including abnormalities in the composition of the blood or urine or abnormalities in imaging tests

  • GFR < 60 mL per minute per 1.73 m2 for three months or more, with or without kidney damage

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Diagnostic Criteria for Kawasaki Disease (KD)

Kawasaki disease (KD) is a childhood vasculitis affecting the medium-sized muscular arteries, mainly the coronary arteries. The hallmark of KD is fever lasting 5 days or more, counting the day of fever onset as day 1, in addition to 4 or 5 of the principal clinical criteria: cracking of lips or strawberry tongue, nonpurulent conjunctivitis, rash, erythema and edema of the hands and feet, and large unilateral cervical lymphadenopathy. Continue reading “Diagnostic Criteria for Kawasaki Disease (KD)”

ICSD Revised Classification of Adult Insomnia

Primary Insomnia

  • Idiopathic insomnia: Insomnia arising in infancy or childhood with a persistent, unremitting course
  • Psychophysiologic insomnia: Insomnia due to a maladaptive conditioned response in which the patient  learns to associate the bed environment with heightened arousal rather than sleep; onset often associated with an event causing acute insomnia, with the sleep disturbance persisting despite resolution of the precipitating factor
  • Paradoxical insomnia (sleep-state misperception): Insomnia characterized by a marked mismatch between the patient’s description of sleep duration and objective polysomnographic findings Continue reading “ICSD Revised Classification of Adult Insomnia”

New Diagnostic Criteria for Myocardial Infarction (MI)

Criteria for acute, evolving or recent MI

Either one of the following criteria satisfies the diagnosis for an acute, evolving or recent MI:

1) Typical rise and gradual fall (troponin) or more rapid rise and fall (CK-MB) of biochemical markers of myocardial necrosis with at least one of the following:

Continue reading “New Diagnostic Criteria for Myocardial Infarction (MI)”

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