Autoimmune lymphoproliferative syndrome (ALPS) is characterized by dysregulation of the immune system due to an inability to regulate lymphocyte homeostasis through the process of lymphocyte apoptosis (a form of programmed cell death). The consequences of this include lymphoproliferative disease, manifested by lymphadenopathy, hepatomegaly, splenomegaly, and an increased risk of lymphoma, as well as autoimmune disease, typically involving blood cells.
Criteria
Diagnostic Criteria for Thyroid Storm
Burch and Wartofsky have delineated a point system assessing degrees of dysfunction in various systems (thermoregulatory, central nervous, gastrointestinal, and cardiovascular).
Diagnostic Criteria for Small Fibre Neuropathy (SFN)
Small fiber neuropathy manifests in a variety of different diseases and often results in symptoms of burning pain, shooting pain, allodynia, and hyperesthesia.
Clinical Criteria for Bell’s Palsy (Idiopathic Facial Nerve Paralysis)
Bell’s palsy is a peripheral palsy of the facial nerve that results in muscle weakness on one side of the face.
Diagnostic Criteria for Refractory Ascites
Refractory ascites is defined as ascites that does not recede or that recurs shortly after therapeutic paracentesis, despite sodium restriction and diuretic treatment.
Diagnostic Criteria for Psoriatic Arthritis (PsA)
Psoriatic arthritis is a type of arthritis that develops in some people with the skin condition psoriasis. It typically causes affected joints to become inflamed (swollen), stiff and painful.
Clinical Diagnostic Criteria for Hospital-Acquired (or Nosocomial) Pneumonia (HAP)
Acute nosocomial pneumonia is broadly defined as pneumonia characterized by a new and persistent infiltrate (radiographically present for greater than 48 hours) PLUS one of the following:
Criteria for Brain Death in Adults and Children
Physicians, health care workers, members of the clergy, and laypeople throughout the world have accepted fully that a person is dead when his or her brain is dead.
Diagnostic Criteria for Cholangitis
Acute cholangitis, also referred to as ascending cholangitis, is an infection of the biliary tree characterized by fever, jaundice, and abdominal pain, which in most cases is the consequence of biliary obstruction. Diagnosis is commonly made by the presence of clinical features, laboratory tests, and imaging studies.
Diagnostic Criteria of Acute Disseminated Encephalomyelitis (ADEM)
Acute Disseminated Encephalomyelitis (ADEM) is a brief but intense attack of inflammation (swelling) in the brain and spinal cord and occasionally the optic nerves that damages the brain’s myelin (the white coating of nerve fibers).